SOFA Score Calculator

The Sequential Organ Failure Assessment (SOFA) score grades dysfunction in six organ systems, respiration, coagulation, liver, cardiovascular, central nervous system, and renal, each from 0 to 4. The subscores add up to a total of 0 to 24, where higher means more severe organ failure. It was introduced by Vincent and colleagues in 1996 to describe and track organ dysfunction in critically ill patients, especially those with sepsis.

Respiration uses the PaO2/FiO2 ratio (with the 3 and 4 point bands requiring respiratory support), coagulation uses the platelet count, liver uses bilirubin, cardiovascular uses mean arterial pressure or the vasopressor dose, the CNS score uses the Glasgow Coma Scale, and renal uses creatinine or urine output. This calculator scores each system on entry and sums them. For the renal system it takes the worse of the creatinine band and the urine-output band.

Under the 2016 Sepsis-3 criteria, sepsis is defined as a suspected or confirmed infection plus an acute rise in the SOFA score of 2 points or more from baseline. In a patient with no known prior organ dysfunction, the baseline is assumed to be 0. The change from baseline, not a single absolute value, is what carries the diagnostic weight, so tracking the score over time matters.

Higher maximum SOFA scores are associated with higher ICU mortality in published cohorts: roughly under 10% at a total of 0 to 6, about 15 to 20% at 7 to 9, about 40 to 50% at 10 to 12, and over 80% at scores of 15 and above. These are population estimates from groups like the cohort in Ferreira et al. (2001), not predictions for any one patient. The trend in the score over the first days of admission is often more informative than the value on any single day.

This calculator uses US conventional units: PaO2 in mmHg, FiO2 as a fraction (0.21 for room air, 0.50 for 50% oxygen), platelets in thousands per microliter, bilirubin and creatinine in mg/dL, mean arterial pressure in mmHg, and urine output in mL per day. Vasopressor doses follow the original SOFA thresholds in micrograms per kilogram per minute. Enter the Glasgow Coma Scale as a whole number from 3 to 15.

No. It is for education and quick reference only and is not a substitute for professional medical advice, diagnosis, or treatment. The SOFA score is one input among many in critical care and should be interpreted alongside the full clinical picture and the judgment of a qualified clinician. Do not use it to make treatment decisions on your own.